Friday, October 15, 2010

History Of Penicillin



penicillin


Alexander Fleming was the first one to discover penicillin. In 1875 John Tyndall was conduct one experiment.Tyndall prepared 100 tubes of broth, placed them comparatively close to each other. He kept the tubes open in order to be exposed to the air for 24 hours. Alexander Fleming accidentally rediscovered penicillin.Fleming noticed a halo of inhibition of bacterial growth around a contaminant blue-green mold staphylococcus plate culture. Fleming concluded that the mold was releasing a substance that was inhibiting bacterial growth and lysing the bacteria. this substance was nothing but the penicillin antibiotic.

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Thursday, October 7, 2010

IMPORTANT LINKS FOR PHARMACY

Pdf related to antibiotics

penicillin

http://www.botany.hawaii.edu/faculty/wong/BOT135/Lect20.pdf
http://www.medsafe.govt.nz/Profs/Datasheet/p/penicillinginj.pdf
http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/050141s226lbl.pdf
http://archinte.ama-assn.org/cgi/reprint/162/7/822.pdf
http://www.pfizer.com/files/products/uspi_permapen.pdf
http://lhncbc.nlm.nih.gov/lhc/docs/published/2001/pub2001051.pdf
http://nobelprize.org/nobel_prizes/chemistry/laureates/1965/woodward-lecture.pdf
http://ajph.aphapublications.org/cgi/issue_pdf/advertising_pdf/34/10.pdf
http://bmb.oxfordjournals.org/content/6/3/264.3.full.pdf
http://www.drsfostersmith.com/Rx_Info_Sheets/rx_penicillin_g.pdf
http://www.urmc.rochester.edu/medicine/genetics/media/documents/penicil1.pdf
http://aac.asm.org/cgi/reprint/39/5/1127.pdf
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Enzyme_Assay/penicillinamidase.Par.0001.File.dat/penicillinamidase.pdf
http://www.pharmweb.net/pwmirror/library/tlc/T108-141.pdf
http://www.state.il.us/HPA/Illinois%20History/klaus106.pdf
http://www.jiaci.org/issues/vol17issue02/9.pdf
http://www.annals.org/content/141/1/I-48.full.pdf
http://www.cdc.gov/ncidod/eId/vol10no6/pdfs/03-0488.pdf
http://aac.asm.org/cgi/reprint/41/5/1210.pdf
http://www.dhh.louisiana.gov/offices/miscdocs/docs-249/vet/penicillin.pdf
http://www.jbc.org/content/144/1/285.full.pdf
http://www.springerlink.com/content/q72056234147p772/
http://jds.fass.org/cgi/reprint/48/5/541.pdf
http://www.fda.gov/downloads/AnimalVeterinary/Products/ApprovedAnimalDrugProducts/FOIADrugSummaries/ucm064830.pdf
http://www.nejm.org/doi/full/10.1056/NEJM200501063520122
http://archinte.highwire.org/cgi/reprint/140/8/1117.pdf
http://www.ncfar.org/penicillin.pdf
http://journals.lww.com/pidj/Citation/2004/06000/Safety_of_Cold_Adapted_Live_Influenza_Vaccine.30.aspx
http://www.rivier.edu/journal/ROAJ-Fall-2007/J109-Derderian.pdf
http://www.pnas.org/content/73/6/1816.full.pdf
http://chestjournal.chestpubs.org/content/64/3/358.full.pdf
http://www.e-journals.in/open/vol4/no4/0425-536-545.pdf
https://kb.osu.edu/dspace/bitstream/1811/3443/1/V44N06_278.pdf
http://www.jimmunol.org/cgi/reprint/107/1/302.pdf
http://adc.bmj.com/content/55/11/857.full.pdf
http://www.ejbjs.org/cgi/reprint/52/1/95.pdf
http://medres.med.ucla.edu/Education/QOW/1st%20use%20PCN%20in%20US.pdf
http://www.clinchem.org/cgi/reprint/30/6/908.pdf
http://www.nil.wustl.edu/labs/raichle/MER_papers/2_Neurotoxicity%20of%20Intrvenously%20Administered%20Penicillin%20G.pdf

Cephalosporin

http://www.aaaai.org/members/academy_statements/position_statements/cephalosporin_paper.pdf
http://www.sonny2.com/articles/cephalosporin.pdf
http://www.annals.org/content/141/1/I-48.full.pdf+html
http://www.avma.org/advocacy/federal/regulatory/practice_issues/drugs/cephalosporin.pdf
http://www.medigraphic.com/pdfs/lamicro/mi-2007/mi07-3_4g.pdf
http://www.health.gov.il/units/pharmacy/trufot/alonim/795.pdf
http://www.ama-assn.org/ama1/pub/upload/mm/370/measure21-specification.pdf
http://us.gsk.com/products/assets/us_zinacef.pdf
http://www.accessdata.fda.gov/drugsatfda_docs/label/2004/50461slr139_ancef_lbl.pdf
http://www.skinandaging.com/files/docs/Extensions_Wint05.pdf
http://www.fda.gov/downloads/Drugs/DevelopmentApprovalProcess/Manufacturing/UCM193419.pdf
http://www.ptolemy.ca/members/archives/2007/c-section/hopkins1999.pdf
http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/0550585s063lbl.pdf
http://homepage.vghtpe.gov.tw/~jcma/73/4/181.pdf
http://www.taxonomicoutline.org/index.php/mmg445/article/view/63/44
http://www.fda.gov/OHRMS/DOCKETS/dockets/06p0461/06p-0461-cp00001-04-attachment-03-vol1.pdf
http://aac.asm.org/cgi/reprint/48/1/53.pdf
http://aem.asm.org/cgi/reprint/AEM.00129-07v1.pdf
http://www.auburn.edu/~deruija/Cephrev.pdf
http://www.lupinpharmaceuticals.com/pdf/Cephalexin%20Suspension%20USP_May%202005_207064.pdf
http://www.sagentpharma.com/Products/Cefoxitin/Catalog/Cefoxitin_PI1.pdf
http://www.us.sandoz.com/site/en/company/news/pool/Ceftriaxone%20Enlarged.pdf
http://www.elan.com/images/Maxipime_Factsheet_200204_tcm10-23008.pdf
http://www.jfponline.com/pdf/5502/5502JFP_AppliedEvidence1.pdf
http://www.biomedcentral.com/content/pdf/1476-0711-3-13.pdf
http://www.cdph.ca.gov/HealthInfo/discond/Documents/Gonorrhea-Treatment-Guides-Dec-2006.pdf
http://www.cdc.gov/ncidod/EID/vol9no10/pdfs/03-0179.pdf
http://www.domainvc.com/PDF/Cerexa%20Phase%202%20initiation%20-%2010_19_05.pdf
http://www.bdjpharmacol.com/0302/80.pdf
http://wvc.omnibooksonline.com/data/papers/2009_S4B.pdf
http://aem.asm.org/cgi/reprint/AEM.01188-08v1.pdf
http://www.dionex.com/en-us/webdocs/70915-lpn_2209-01.pdf
http://www.jnjpharmarnd.com/jnjpharmarnd/assets/news_release_11132008.pdf
http://pediatrics.aappublications.org/cgi/reprint/122/6/1212.pdf
http://www.nfid.org/pdf/pediatric_archive/cephalosporinsupdate.pdf
http://www.sld.cu/galerias/pdf/sitios/apua-cuba/p13-prophylactic_antibiotics.pdf
http://extranet.acsysweb.com/vSiteManager/StamfordHospital/Public/Upload/Antimicrobial_Pamphlet_2009.pdf
http://www.cdc.gov/std/treatment/2006/GonUpdateApril2007.pdf
http://www.vhpharmsci.com/Presentations/2010/Gorillacillins%20in%20ICU-T%20Lau%20(MAR10).pdf
http://www.consumerreports.org/health/resources/pdf/clinical-guidelines/sr-sinusitis--acute--0511.pdf
http://www.who.int/selection_medicines/committees/subcommittee/2/cefalexin_new.pdf
http://www.shreya.co.in/pdf/XTUM_PM_2007_01.pdf
http://us.gsk.com/products/assets/us_ceftin.pdf
http://www.turner-white.com/pdf/jcom_jul02_overview.pdf
http://ejournal.sinica.edu.tw/bbas/content/2009/2/Bot502-07.pdf
http://www.oxfordjournals.org/our_journals/jac/press_releases/mar07.pdf
http://www.convenia.com/pdfs/Convenia_prescribing_information.pdf