Monday, November 1, 2010

Mode of action of penicillin

mode of action 


       beta-lake formation of antibiotics to prevent work on the bacterial membrane peptidoglikan crossbowmen link. The root of beta-lake (group work) this enzyme, (DD-transpeptidase) penicillin peptidoglikan linking molecules in the bacteria, which weakens the bacterial membrane (ie, in the case of the death of antibiotics sitolisis What Angiospermae). Also it makes a lot of precursor activation peptidoglikan bacterial autolysins, and hydrolase are also bacteria that digest membrane peptidoglikan now.

       protoplasts of Gram-positive bacteria alleged loss of cell wall. cell walls of Gram-negative bacteria, which do not lose the sequence is lost after he was called to bring aid to penicillin.

       Penicillin showed synergistic inhibition of aminoglycoside and allow it to penetrate the synthesis of aminoglycoside peptidoglikan easier running the department suffering from bacterial bacterial protein synthesis in cells. This follows the cast down by organisms in the MBC to raise.

       Penicillin antibiotics such as beta-other lake not only prevent the distribution of bacteria, but also the distribution of Cyanobacteria cyanelles glaucophytes limited and out of the photosynthetic organelles and out of the chloroplast DETAIL of bryophytes. But for non-angiosperm from plastida be punished again. This is the reason for the discovery of evolution contain endosymbiotic plastid division of land to crops.




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